Lead & Scientist
Email: [email protected]
Dr. Firdausi Qadri, an international scientist at the Centre for Vaccine Sciences in International Centre for Diarrheal Disease Research, Bangladesh (icddr,b), has been working in collaboration with international and national organizations on research related to infectious diseases and vaccine development over the last 25 years. She and her team devote their time in conducting research on diarrheal pathogens, such as Vibrio cholerae and enterotoxigenic Escherichia coli (ETEC) so that vaccines can be formulated to save the lives of children suffering from diarrheal diseases. Emphasis has also been placed on understanding the immune response in H.pylori-infected people in Bangladesh and patient responses to typhoid fever and vaccines. Intensive research has been carried out in the field of enteric diseases, specifically in the areas of immunology, genomics, proteomic technology and diagnostics, and vaccine development. There is an active quest to understand the immunological responses in natural infections as well as in vaccines to better discern factors that need to be improved in current and future formulations. On 28 November 2014, UN Secretary General Ban Ki-moon appointed Dr. Firdausi Qadri and nine members to a high-level advisory panel on the proposed UN Technology Bank aimed at helping the world’s least developed countries overcome poverty. Dr. Qadri is a founding member and Chairman of ideSHi.
Noor FA, Sultana N, Bhuyan GS, Islam MT, Hossain M, Sarker SK et al. Nationwide carrier detection and molecular characterization of β-thalassemia and hemoglobin E variants in Bangladeshi population. Orphanet Journal of Rare Diseases. 2020; doi.org/10.1186/s13023-020-1294-z
Sarker SK, Islam MT, Hasib SH, Sultana N, Hossain SR, Biswas A et al. A novel missense mutation of Isovaleryl-CoA dehydrogenase gene associated with chronic intermittent Isovaleric acidemia in a Bangladeshi patient. Meta Gene. 2019; doi.org/10.1016/j.mgene.2019.100557
Begum MN, Islam MT, Hossain SR, Bhuyan GS, Halim MA, Shahriar I et al. Mutation Spectrum in TPO Gene of Bangladeshi Patients with Thyroid Dyshormonogenesis and Analysis of the Effects of Different Mutations on the Structural Features and Functions of TPO Protein through In Silico Approach. BioMed Research International. 2019; 10.1155/2019/9218903
Sarker SK, Islam MT, Biswas A, Bhuyan GS, Sultana R, Sultana N et al. Age-Specific Cut-off Values of Amino Acids and Acylcarnitines for Diagnosis of Inborn Errors of Metabolism Using Liquid Chromatography Tandem Mass Spectrometry. BioMed Research International. 2019; 10.1155/2019/3460902
Islam MT, Sarker SK, Shithi ST, Bhuyan GS, Rahat A, Islam NN et al. High resolution melting curve analysis enables rapid and reliable detection of G6PD variants in heterozygous females. BMC Genetics. 2018;19(1).
Sarker SK, Islam MT, Bhuyan GS, Sultana N, Begum MN, Al Mahmud-Un-Nabi M et al. Impaired acylcarnitine profile in transfusion-dependent beta-thalassemia major patients in Bangladesh. J. Adv. Res. 2018;12:55-66.
Islam MT, Sarker SK, Sultana N, Begum MN, Bhuyan GS, et al. (2018) High resolution melting curve analysis targeting the HBB gene mutational hot-spot offers a reliable screening approach for all common as well as most of the rare beta-globin gene mutations in Bangladesh. BMC Genetics 19:1 doi:10.1186/s12863-017-0594-3
Bhuyan GS, Hossain MA, Sarker SK, Rahat A, Islam MT, et al. (2017) Bacterial and viral pathogen spectra of acute respiratory infections in under-5 children in hospital settings in Dhaka city. PLOS ONE 12(3): e0174488. doi: 10.1371/journal.pone.0174488
Al‐Mamun MM, Sarker SK, Qadri SK, Shirin T, Mohammad QD, LaRocque R, Karlsson EK, Saha N, Asaduzzaman M, Qadri F, Mannoor MK. Examination of Huntington’s disease with atypical clinical features in a Bangladeshi family tree. Clinical Case Reports. 2016 Dec 1;4(12):1191-4.
Sarker SK, Islam MT, Eckhoff G, Hossain MA, Qadri SK, Muraduzzaman AK, Bhuyan GS, Shahidullah M, Mannan MA, Tahura S, Hussain M. Molecular Analysis of Glucose-6-Phosphate Dehydrogenase Gene Mutations in Bangladeshi Individuals. PloS one. 2016 Nov 23;11(11):e0166977.
Qadri F, Ali M, Chowdhury F, Khan AI, Clemens JD et al. Feasibility and effectiveness of the oral cholera vaccine, in an urban “cholera-endemic” setting in Bangladesh: a cluster-randomised non-blinded trial. The Lancet. 2015.
Qadri F, Wierzba TF, Ali M, Chowdhury F, Khan AI, Saha A, Khan IA, Asaduzzaman M, Akter A, Khan A, Begum YA. Efficacy of a single-dose, inactivated oral cholera vaccine in Bangladesh. New England Journal of Medicine. 2016 May 5;374(18):1723-32.
Bhuiyan TR, Hoq MR, Nishat NS, Al Mahbuba D, Rashu R, Islam K, Hossain L, Dey A, Harris JB, Ryan ET, Calderwood SB. Enumeration of Gut-Homing β7-Positive, Pathogen-Specific Antibody-Secreting Cells in Whole Blood from Enterotoxigenic Escherichia coli-and Vibrio cholerae-Infected Patients, Determined Using an Enzyme-Linked Immunosorbent Spot Assay Technique. Clinical and Vaccine Immunology. 2016 Jan 1;23(1):27-36.
Clemens JD, Qadri F. Cholera in Bangladesh. Weekly epidemiological record, WHO. No 40, 2015.90: 517-544.
Chowdhury F, Mather AE, Begum YA, Asaduzzaman M, Baby N, Sharmin S, Biswas R, Uddin MI, LaRocque RC, Harris JB, Calderwood SB. Vibrio cholerae serogroup O139: isolation from cholera patients and asymptomatic household family members in Bangladesh between 2013 and 2014. PLoS Negl Trop Dis. 2015 Nov 12;9(11):e0004183.